Figure 7.

Effect of SB203580 on LPS stimulated NO production. Concentration dependent effect of the p38 MAPK inhibitor SB203580 (0–10 μM) on LPS (1 μg/ml)-stimulated NO production measured at 24 hours. Cells were stimulated and the culture medium harvested and assayed for nitrite content by Greiss assay. The data show that SB203580 was able to inhibit LPS-stimulated NO production. Results for the effects of the inhibitor are expressed mean ± SEM, ***p < 0.001 vs no inhibitor, n = 6.