Table 2

Total and differential cell counts of BAL fluid from MMP-12 -/- and WT mice 14 days after intranasal administration of bleomycin (BLM) or saline vehicle (Control). Results are presented as the mean (.103 cells) ± SEM. n: number of mice. a: P < 0.05, b: P < 0.01, c: P < 0.001 compared with control mice exposed to saline solution only.

Treatment
Strain
N
Total cells
Macrophages
Neutrophils
Eosinophils
Lymphoytes

Control
WT
5
579 ± 92
561 ± 79
13 ± 10
0 ± 0
6 ± 6

MMP-12 -/-
5
547 ± 92
540 ± 94
2 ± 2
0 ± 0
4 ± 4
BLM
WT
8
2204 ± 284c
1783 ± 210c
285 ± 78b
55 ± 19b
81 ± 33b

MMP-12 -/-
8
1352 ± 355a
1152 ± 255a
104 ± 62b
19 ± 17
76 ± 55

Manoury et al. Journal of Inflammation 2006 3:2   doi:10.1186/1476-9255-3-2