Table 8

Sequential VAS – Pain Index

Group

Baseline

Week 1

Week 2

Week 4

Week 6

Week 8

Placebo

72.9 ± 2.1

71.4 ± 2.7

68.4 ± 3.2

63.9 ± 3.3 **

58.6 ± 3.9 **

52.0 ± 4.7 ***

A

72.9 ± 3.0

66.8 ± 3.3

62.5 ± 4.7 **

51.2 ± 5.0 ***

49.7 ± 5.1 ***

42.7 ± 5.2 ***

B

70.1 ± 2.5

65.8 ± 3.2

58.9 ± 3.8 **

52.0 ± 4.7***

51.9 ± 5.0 ***

44.6 ± 4.9 ***

C

70.7 ± 2.4

65.0 ± 2.6

60.7 ± 2.9 **

52.7 ± 2.5 ***

47.2 ± 3.4 ***

43.4 ± 3.8 ***

Data expressed as mean ± sem. Group A = High dose sierrasil (n = 20), Group B = Low dose sierrasil (n = 21), Group C = Low dose sierrasil + cat's claw extract (n = 25), placebo n = 22. All groups displayed a significant change over the 8 weeks of the study (p < 0.001, ANOVA). Using a Wilcoxan matched pairs Signed-Rank test from baseline; * p < 0.05, ** p < 0.01, *** p < 0.001.

Miller et al. Journal of Inflammation 2005 2:11   doi:10.1186/1476-9255-2-11